Gene discovered for form of brittle bone disease

Researchers at the National Institutes of Health have discovered that a previously unexplained fatal form of Osteogenesis Imperfecta (a disorder that weakens bones and which may cause frequent fractures) results from a genetic defect in a protein involved in the production of collagen.

The study appears in the December 28, 2006 New England Journal of Medicine.

The affected gene contains t…

Arthritis pain, the brain, and the role of emotions

Arthritis pain is processed in brain areas concerned with emotions and fear…… finds Study, indicating target for pain-relieving therapies.

How does the brain process the experience of pain?

Thanks to advances in neuroimaging, we now know the answer lies in a network of brain structures called the pain matrix. This matrix contains two parallel systems. The medial pain system processes…

Neurosurgeon invents laser-guided spine localizer

The Laser-Guided Spine Localizer is the latest innovation in minimally invasive spinal surgery. The localizer is the invention of Dr. Peyman Pakzaban, M.D., a neurosurgeon affiliated with Bayshore Medical Center in Pasadena, Texas.

The goal of minimally invasive spinal surgery is to make the smallest incision possible, avoiding major tissue dissection and trauma for the patient. The smaller …

Tips for an active lifestyle

It may seem surprising to some, but many of today’s grandparents are more likely to be found hiking with their grandchildren than baking cookies, and many of these older people are turning to supplements such as glucosamine, chondroitin and MSM to make sure they can.

As baby boomers age, they want to stay younger longer, which includes maintaining joint health to continue an active lifestyle…

Electronic switch opens doors in Rheumatoid joints

A breakthrough in understanding the way atoms move across cell membranes in the human body could pave the way for the development of new treatments for inflammatory diseases such as rheumatoid arthritis.

Scientists at the University of Leeds have identified a previously unknown natural mechanism that opens ion channels – proteins at the cell surface that act as doorways into and out of cells…

In-vitro models minimize animal use in arthritis studies

Researchers at the University of Missouri-Columbia’s Comparative Orthopaedic Laboratory (COL) have developed an in vitro model using small sections of joint capsule and cartilage typically discarded that mimics arthritic joints. This “joint in a test tube” model can be used to investigate causes and mechanisms for the development and progression of arthritis and to screen new treatments such as…

Bionic nerve to bring damaged limbs and organs back to life

Researchers in the School of Medicine have transformed fat tissue stem cells into nerve cells and now plan to develop an artificial nerve that will bring damaged limbs and organs back to life.
Dr Paul Kingham and his team at the UK Centre for Tissue Regeneration (UKCTR) isolated the stem cells from the fat tissue of adult animals and differentiated them into nerve cells to be used for repair a…

Research for healthier bones

In Australia, one in two women and one in three men over the age of 60 will sustain a bone fracture. It is also estimated that the death rate in women from hip fractures is greater than the incidence of all female cancers combined. Osteoporosis, or ‘porous bones’, is a disease where bone density and structural quality deteriorate, leading to an increased risk of fracture. Common sites are the w…

Acupuncture may help relieve Fibromyalgia symptoms

Acupuncture helped relieve symptoms such as pain and depression in women with the chronic pain disorder FIBROMYALGIA, according to research presented at the annual meeting of the American College of Rheumatology.

“Patients not getting enough results from drug therapy should try honest acupuncture,” said lead author Dr. Daniel Feldman, head of rheumatology at the Federal University of Sao Pau…