Gene discovered for form of brittle bone disease
Researchers at the National Institutes of Health have discovered that a previously unexplained fatal form of Osteogenesis Imperfecta (a disorder that weakens bones and which may cause frequent fractures) results from a genetic defect in a protein involved in the production of collagen.
The study appears in the December 28, 2006 New England Journal of Medicine.
The affected gene contains t…