Study identifies novel role for a protein that could lead to new treatments for rheumatoid arthritis

A new study by rheumatologists at Hospital for Special Surgery in New York has shown that a powerful pro-inflammatory protein, tumor necrosis factor (TNF), can also suppress aspects of inflammation. The researchers say the identification of the mechanism of how this occurs could potentially lead to new treatments for diseases such as rheumatoid arthritis.

“Prior to this study, TNF has long b…

Advances in treatment of musculoskeletal disorders

At the September conference of ‘Frontiers in Medicine’ (sponsored by Scripps Foundation for Medicine and Science), the presentations highlighted innovative materials and procedures designed to improve the quality of life for millions of Americans suffering from musculoskeletal diseases.

A New Era in Joint Replacement Materials

Dr. Clifford W. Colwell. Jr., director of the Scripps Clinic C…

Keep on typing

Computer programmers, office workers, college students and Internet addicts everywhere can now breathe a sigh of relief: there is better evidence that genetics rather than hand use is the cause of carpal tunnel syndrome (CTS).

A new study recently presented at the 74th Annual Meeting of the American Academy of Orthopaedic Surgeons indicates that the causal link between CTS and repetitive use…

Biology of broken bones leads to new treatments

A review of research into how cells and proteins repair fractured bones published in the November 2008 issue of The Journal of the American Academy of Orthopaedic Surgoeons demonstrates that understanding the biology behind this healing process may lead to improved and less invasive treatments for fractures.

“The healing of a fracture takes place at the injury site and at other points in the…

Mind – Body – Medicine

Mind-body medicine focuses on the interactions among the brain, mind, body, and behavior, and the powerful ways in which emotional, mental, social, spiritual, and behavioral factors can directly affect health.

It regards as fundamental an approach that respects and enhances each person’s capacity for self-knowledge and self-care, and it emphasizes techniques that are grounded in this approac…

Sex plays a role in orthopaedics

There is no debate that males and females are different, but there has been limited comprehension of the influence of sex on disease.

Osteoarthritis affects more than forty million Americans and more than a quarter of the population between the ages of 45 and 64 years old. The disease is progressive, painful and currently incurable. In a special J. Robert Gladden Society supplement of the Jo…

Researchers disclose key advance in treating spinal cord injuries

Research from a team of scientists from the University of Rochester Medical Center and the University of Colorado Denver School of Medicine, published in the Journal of Biology, may lead to improved spinal cord repair methods that pave the way for victims of paralysis to recover the use of their bodies without the risk of transplant-induced pain syndromes.

The research focuses on a major sup…

Chronic back pain linked to changes in the brain

A German research team, using a specialized imaging technique, revealed that individuals suffering from chronic low back pain also had microstructural changes in their brains. The findings were presented at the annual meeting of the Radiological Society of North America (RSNA).

The researchers, led by Jürgen Lutz, M.D., a radiology resident at University Hospital, Ludwig-Maximilians Universi…

Winning by a nose

Cells from the human nose are showing further promise in remediating spinal cord injury, according to research from the University of New South Wales.

Six weeks after injecting cells from the human nose (olfactory ensheathing glia) into the injured spinal cords of rats, the researchers found improvements in the animals’ movement.

“We found improvements in hind limb function of these anima…